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Increased skeletal muscle oxidative capacity is associated with improved glucose tolerance and insulin sensitivity and reduced obesity (Donnelly et al., 2013), thus we hypothesized that synthetic ERR agonists that increase their transcriptional activity above their very high constitutive level may hold significant utility in the treatment of metabolic syndrome

Laboratory Research

Treatment Options:Set of 6 Injections

Originally developed by Metabolic Pharmaceuticals in Australia during the late 1990s and early 2000s, it underwent rigorous Phase I, Phase II, and Phase IIb clinical trials aimed at securing FDA approval as an anti-obesity pharmaceutical