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In addition, GSH has been shown to regulate nitric oxide homeostasis (Hogg, 2002), modulate the activity of proteins by post-translational modification (protein S-glutathionylation) (Pompella et al., 2003), and modulate the activity of neurotransmitter receptors (Oja et al., 2000)

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The MAPK 26,27 , JAK/STAT 28 , and TGF-β 29 pathways exhibit highly conserved mechanisms in the regulation of immunity, lifespan, and aging from C