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BPC-157 is a 15-residue gastric peptide studied for effects on growth-factor receptor signaling, particularly VEGFR2 and the nitric oxide pathway
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Notably, FOXO4-DRI worsened CV outcomes in animal models of pulmonary arterial hypertension by promoting unfavorable vascular wall remodeling [38] , whereas BPTES and GPNMB interventions both had favorable effects on plaque pathology in atherosclerotic animals [194,195]
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