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in animal models, BPC-157 counteracted lesions induced by NO-blocking agents while also modulating the effects of NO-promoting substrates, suggesting the peptide acts as a balancing modulator rather than a simple up- or down-regulator (Sikiric et al., Current Neuropharmacology , via NCBI PMC)
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A peptide encoded in mitochondrial DNA scores higher than one stimulating a hormone that influences metabolism that in turn affects energy use
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