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AOD-9604 Safety: What the Clinical Trials Actually Show

12/15-Lipoxygenase induces cell death in murine fibroblasts, whereas GPX4 rescues cells from lipoxygenase-induced cell death.5 But in other settings, lipoxygenases and GPX4 biochemically cooperate: lipoxygenases generate highly reactive peroxidation products of unsaturated fatty acids (P-O-O-H) that are prone to further uncontrolled lipid membrane peroxidation

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Size:2 fl oz

doi:10.2337/dc19-S009 ADA

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