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Overall, this study not only investigates the mechanisms of ferroptosis and its interaction with natural flavonoids but also emphasizes the application details of these compounds in preclinical CNS disease models, providing new insights and opportunities for improving CNS disease prognosis and developing neuroprotective agents
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We thank Joanna Loizou and Anna Schrempf for providing p53 mutant human TERT-immortalized retinal pigment epithelial 1 (RPE1) cells
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