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Endocytic pathways represent the predominant route of PEVs internalization, with vesicles from Bacteroides thetaiotaomicron internalized into epithelial cells via dynamin-dependent endocytosis, subsequently trafficked to LAMP-1⁺ endo-lysosomal compartments and redistributed to perinuclear regions, 142 and comparable routes reported for bifidobacterial EVs 143 and Lactiplantibacillus plantarum EVs through clathrin-mediated endocytosis
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Vimentin is a dominant target of in situ humoral immunity in human lupus tubulointerstitial nephritis
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