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In contrast, ML385 exploits an alternative mechanism by binding to the DNA binding domain of NRF2 and shows significant chemosensitizing activity, specifically in non-small cell lung cancer cells harboring KEAP1 mutations (209)
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Quantity:50kg
In case of ethyl methanesulfonate mutants, the region surrounding the expected point mutation was amplified by PCR and the single point mutation was verified by sequencing
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