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The former showed positive differences with physical function, while the latter showed negative differences with energy/fatigue, physical health, general health, and pain, as shown in Table 2

protocol

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530 Model interpretability and biological significance Many high-performance AI models, particularly deep learning, suffer from key challenges including risks of overfitting in high-dimensional data, biases introduced by imbalanced or non-representative datasets, and the difficulty of interpreting complex models because of “black box” that make it difficult to explain the biological mechanisms behind their predictions