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Periodic boundary conditions were established with a box size of 125 Γ 125 Γ 119 Γ 75
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There are numerous pores with a diameter of about 70β100 nm on it ( Since the kidney is the most important organ for elimination and excretion, many potential therapeutic agents cannot achieve a desired therapeutic effect because of their poor pharmacokinetics and short retention time in the kidneys (Liu C.-P
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